Canadian Business magazine estimated Mr Sherman to be worth $4.77 billion Canadian (£2.78bn), making him the 15th richest Canadian. He stepped down as chief executive in 2012, but stayed on as executive chairman.
They are releasing few details at this point, saying the investigation is still in the early stages and the circumstances of their death appear suspicious and we are treating it that way.
"Our investigators are inside investigating and taking apart the scene".
Sherman founded the Toronto-based Apotex Inc.in 1974 with two employees and gradually turned it into the largest Canadian-owned pharmaceutical company.
The company, which made its name producing generic drugs, grew to employ more than 11,000 people worldwide.
Honey Sherman sat on the boards of several hospital, charitable and Jewish foundations, and last month was awarded a Senate medal for community service. In the acquisition deal, Sherman reportedly promised to share a mix of royalties and a stake in the company with Winter's four orphaned children.
Hopkinson said the deaths are not now being treated as homicides, adding that more investigation will be necessary.
Police Investigate 'Suspicious' Death of Prominent Toronto Couple
Police later said there were no signs of forced entry at the property and they were not now searching for a suspect, according to CBC.
CrimeOnline will update this story when more information becomes available.
"I am beyond words right now. Our condolences to their family & friends, and to everyone touched by their vision & spirit".
Autopsies are being conducted on the bodies of a billionaire pharmaceutical giant and his wife who were found dead in their York Mills home on Friday afternoon.
Ontario's health minister, Eric Hoskins, described the couple in a tweet as "wonderful human beings, incredible philanthropists, great leaders in healthcare".
Speaking with reporters about the couple on Saturday morning, Mayor John Tory said they were "extraordinary citizens" who "contributed so much to so many in Toronto".
Prince Harry to marry on May 19
According to the BBC , the wedding - including the service, music, flowers and reception - will be paid for by the Royal Family. Mr Knauf said Harry and Ms Markle "want the public to feel part of their day" - and are looking at ways to achieve that.